Table 2—

Multivariate models of IGT incidence in relation to baseline values of insulin resistance, insulin secretion, and intra-abdominal fat area

ModelVariables in the modelOR (95% CI)P
1Intra-abdominal fat areaSee Figure 10.001
BMI0.72 (0.41–1.26)0.252
HOMA-IR2.41 (1.15–5.04)0.019
IIRSee Figure 10.019
FPG0.482
Age0.82 (0.55–1.23)0.339
Female sex2.07 (0.78–5.46)0.143
Intra-abdominal fat × FPGSee Figure 10.003
IIR × FPGSee Figure 10.030
2Same variables as model 1, except total fat area is substituted for BMI
Intra-abdominal fat areaSee Figure 10.003
 Total fat area0.96 (0.50–1.85)0.899
 Intra-abdominal fat × FPGSee Figure 10.005
3Same variables as model 1, except total subcutaneous fat  area is substituted for BMI
 Intra-abdominal fat areaSee Figure 10.003
 Total subcutaneous fat area0.96 (0.52–1.76)0.899
 Intra-abdominal fat × FPGSee Figure 10.005
4Same variables as model 1, except abdominal subcutaneous fat area is substituted for BMI
 Intra-abdominal fat areaSee Figure 10.005
 Abdominal subcutaneous fat area1.23 (0.69–2.17)0.484
 Intra-abdominal fat × FPGSee Figure 10.006
5Same variables as model 1, except waist circumference is  substituted for BMI
 Intra-abdominal fat areaSee Figure 10.001
 Waist circumference0.87 (0.46–1.64)0.665
 Intra-abdominal fat × FPGSee Figure 10.001
  • ORs for continuous variables reflect a 1-SD magnitude increase. In all models, HOMA IR, IIR, and the interaction of IIR by FPG were also associated with the risk of IGT.