Table 1—

Comparison of selected baseline CVD risk factors in nondiabetic individuals according to CVD status at follow-up, the SHS (N = 2,283)

Known or potential CVD risk factorIncident CVD (n = 181)No incident CVD (n = 2,102)P*
Age (years; mean ± SD)60.0 ± 8.355.1 ± 8.0<0.001
Sex (% women)33.159.1<0.001
BMI (kg/m2; mean ± SD)29.0 ± 4.629.8 ± 6.10.027
Waist circumference
 Men100.3 ± 10.9100.6 ± 12.50.787
 Women102.2 ± 12.4102.8 ± 15.50.706
Systolic blood pressure (mmHg)133 ± 21124 ± 18<0.001
Total cholesterol (mg/dl; mean ± SE)192 ± 2.7190 ± 0.820.493
LDL cholesterol (mg/dl; mean ± SE)113 ± 2.3108 ± 0.710.026
HDL cholesterol (mg/dl; mean ± SD)46 ± 1348 ± 150.001
Triglycerides (mg/dl; mean ± SD)127 ± 81127 ± 920.959
Current smoking (%)44.840.20.231
FG (mg/dl; mean ± SD)102 ± 12.0102 ± 11.00.955
FI (μU/ml; mean ± SD)14.2 ± 10.015.6 ± 13.40.087
Log (fibrinogen) (mg/dl; mean ± SD)5.7 ± 0.25.6 ± 0.30.024
Albumin:creatinine ratio (% >30 mg/g)17.710.70.005
HOMA-IR3.6 ± 2.74.0 ± 3.60.084
ATP-III MS (%)§35.934.90.778
Incident diabetes (%)13.817.30.229
  • *

    * P values are for the t test of differences in means or the χ2 test of differences in proportions for continuous and categorical variables, respectively, in comparisons between participants with and without incident CVD;

  • means are adjusted for study center;

  • (FI [μU/ml] · FG [mmol/l])/22.5;

  • §

    § three or more of the following characteristics at baseline: waist circumference >102 cm in men and >88 cm in women; triglycerides ≥150 mg/dl; HDL cholesterol <40 mg/dl in men and <50 mg/dl in women; blood pressure ≥130/85 mmHg; or FG ≥110 mg/dl;

  • any of the following: FG ≥126 mg/dl; self-reported physician-diagnosed diabetes during standardized interview; medication inventory data indicating current use of oral hypoglycemic medications or insulin.