Table 1—

Clinical characteristics of the studied groups

Men
Women
Control-NGTObese-NGTObese-IGTControl-NGTObese-NGTObese-IGT
n171410251820
Age (years) (range)36.00 ± 7.0535.64 ± 10.5537.70 ± 6.4534.12 ± 8.5438.72 ± 9.1638.35 ± 5.83
(24.0–48.0)(21.0–47.0)(23.0–45.0)(23.0–50.0)(21.0–49.0)(25.0–49.0)
BMI (kg/m2) (range)22.80 ± 2.0132.35 ± 3.46*33.24 ± 4.41*21.47 ± 2.1831.99 ± 4.35*34.78 ± 4.59*
(17.78–24.94)(28.15–41.82)(28.03–41.5)(16.82–24.92)(28.09–46.60)(28.28–43.66)
WHR0.83 ± 0.050.95 ± 0.05*0.92 ± 0.07*0.77 ± 0.070.84 ± 0.06*0.87 ± 0.05*
% Body fat16.97 ± 8.7335.78 ± 8.73*35.15 ± 9.62*15.88 ± 5.6736.86 ± 9.75*40.35 ± 8.28*
Fasting glucose (mmol/l)4.95 ± 0.595.50 ± 0.62*6.17 ± 0.64*4.74 ± 0.485.25 ± 0.51*6.10 ± 0.64*
Postload glucose (mmol/l)4.54 ± 0.865.54 ± 1.58*9.18 ± 1.18*4.66 ± 1.035.79 ± 1.25*9.01 ± 0.90*
Insulin (pmol/l)69.43 ± 38.84128.89 ± 81.32*133.60 ± 56.34*67.42 ± 31.0288.25 ± 25159.8 ± 115.9*
HbA1c (%) (range)5.54 ± 0.325.70 ± 0.516.42 ± 0.66*5.26 ± 0.415.78 ± 0.52*6.38 ± 0.60*
(5.2–6.2)(5.1–6.5)(5.2–7.0)(4.6–6.0)(4.9–6.8)(5.4–7.2)
NEFAs (mmol/l)0.407 ± 0.120.492 ± 0.140.583 ± 0.16*0.319 ± 0.110.514 ± 0.16*0.597 ± 0.14*
TC (mmol/l)5.03 ± 1.295.57 ± 1.176.34 ± 1.63*4.15 ± 0.745.35 ± 1.04*5.08 ± 0.98*
TG (mmol/l)1.41 ± 0.812.15 ± 1.05*2.63 ± 2.690.85 ± 0.371.40 ± 0.99*2.07 ± 0.86*
M/FFM (μmol × kg−1 × min−1)46.41 ± 17.1336.38 ± 12.5724.27 ± 8.61*48.62 ± 13.7240.29 ± 12.65*19.16 ± 8.74*
TNF-α (pg/ml)5.33 ± 2.385.78 ± 1.316.93 ± 3.154.59 ± 2.895.81 ± 1.456.46 ± 2.85
sTNFR1 (ng/ml)2.08 ± 0.352.49 ± 0.48*2.61 ± 0.59*1.87 ± 0.382.28 ± 0.38*2.82 ± 0.96*
sTNFR2 (ng/ml)4.36 ± 0.774.84 ± 1.445.86 ± 2.17*4.13 ± 0.824.83 ± 1.12*5.94 ± 2.01*
CRP (mg/l)3.38 ± 1.865.17 ± 2.54*7.29 ± 2.65*3.07 ± 2.124.98 ± 2.36*5.91 ± 2.06*
Leptin (ng/ml)3.42 ± 1.968.56 ± 3.77*8.08 ± 4.15*6.89 ± 4.2619.31 ± 8.55*20.90 ± 9.78*
  • Data are presented as mean ± SD.

  • *

    * P < 0.05 in obese-NGT or obese-IGT groups in comparison with control-NGT group;

  • P < 0.05 in obese-IGT in comparison with obese-NGT group. TC, total cholesterol; TG, triglycerides.