Table 1—

Subject characteristics

Control subjectsType 2 diabetic subjectsP
Age (years)46 ± 248 ± 10.23
Weight (kg)86.8 ± 4.188.2 ± 4.80.82
BMI (kg/m2)25.9 ± 1.028.1 ± 1.40.25
Systolic blood pressure (mmHg)120 ± 2128 ± 60.27
Diastolic blood pressure (mmHg)74 ± 280 ± 30.05*
Fasting plasma glucose (mmol/l)5.21 ± 0.159.07 ± 0.87<0.001*
Fasting plasma insulin (pmol/l)61 ± 487 ± 180.20
HbA1c (%)4.97 ± 0.086.23 ± 0.380.005*
Total cholesterol (mmol/l)5.08 ± 0.224.75 ± 0.380.46
HDL cholesterol (mmol/l)1.39 ± 0.091.02 ± 0.080.01*
LDL cholesterol (mmol/l)3.25 ± 0.202.89 ± 0.330.37
Triglycerides (mmol/l)0.98 ± 0.141.82 ± 0.350.04*
Vo2peak (ml · kg−1 · min−1)27.3 ± 2.028.8 ± 1.40.54
Vo2 during exercise (% Vo2peak)60.6 ± 1.960.0 ± 2.00.84
Workload during exercise (W)91 ± 897 ± 70.55
Mean heart rate during exercise (beats/min)112 ± 5119 ± 40.30
  • Values are expressed as means ± SE. Blood pressures (brachial sphygmomanometry) and fasting plasma glucose and insulin were measured at the initial screening visit. Exercise was at 60% Vo2peak.

  • *

    * P < 0.05 compared with control subjects.