Table 3—

Clinical characteristics of the RANTES promoter and CCR5 genotypes

RANTES −28C/G genotype
RANTES −403G/A genotype
CCR5 59029G/A genotype
G allele(−)G allele(+)A allele(−)A allele(+)A allele(−)A allele(+)
n464152273343126490
M/F (% male)306/158 (66)97/55 (64)183/90 (67)220/123 (64)83/43 (66)320/170 (65)
Age (years)60.2 ± 0.561.2 ± 0.959.7 ± 0.661.1 ± 0.659.3 ± 0.960.8 ± 0.5
Duration (years)12.0 ± 0.411.7 ± 0.811.6 ± 0.612.2 ± 0.511.2 ± 0.812.1 ± 0.4
BMI (kg/m2)23.2 ± 0.223.3 ± 0.323.1 ± 0.223.4 ± 0.223.4 ± 0.323.2 ± 0.2
Hypertension/non-HT (% HT)278/186 (60)84/68 (55)168/105 (62)194/149 (57)76/50 (60)286/204 (58)
HbA1c (%)7.15 ± 0.077.25 ± 0.137.07 ± 0.087.25 ± 0.087.11 ± 0.137.19 ± 0.07
Total cholesterol (mg/dl)194.9 ± 1.7200.2 ± 4.2195.2 ± 2.3197.1 ± 2.3195.2 ± 4.5196.5 ± 1.7
HDL cholesterol (mg/dl)55.3 ± 0.953.5 ± 1.354.9 ± 1.254.9 ± 0.953.9 ± 1.755.1 ± 0.8
Triglycerides (mg/dl)163.2 ± 6.7173.1 ± 21.9157.3 ± 9.0172.4 ± 11.1172.2 ± 24.1164.0 ± 6.9
DR/SDR/PPDR and PDR312/83/6992/33/27186/48/39218/68/5789/19/18315/97/78
Retinopathy (%)(67/18/15)(61/22/17)(68/18/14)(64/20/17)(71/15/14)(64/20/16)
  • Data are the mean ± SE or n (%). HT, hypertensive; NDR, nondiabetic retinopathy; SDR, simple diabetic retinopathy; PPDR, preproliferative diabetic retinopathy; PDR, proliferative diabetic retinopathy.