Table 4—

Distribution of RANTES promoter −28, −403, and CCR5 promoter 59029 genotypes

All subjectsStage of nephropathy
DN0DN1DN2
n616355 (100)166 (100)95 (100)
RANTES −28C/G
  CC464268 (75)133 (80)63 (66)
  CG13880 (23)30 (18)28 (30)
  GG147 (2)3 (2)4 (4)
 G allele frequency (%)13131119
 G(+) genotype: P = 0.0268 (DN0 and 1 vs. 2)
RANTES −403G/A
  GG273154 (43)80 (48)39 (41)
  GA263154 (43)69 (42)40 (42)
  AA8047 (14)17 (10)16 (17)
 A allele frequency (%)34353138
CCR5 59029G/A
  GG12685 (24)27 (16)14 (15)
  GA315173 (49)86 (52)56 (59)
  AA17597 (27)53 (32)25 (26)
 A allele frequency (%)54525856
 A(+) genotype: P = 0.0123
 (DN0 vs. 1 and 2)
  • Genotype data are the number (%) of patients.