Table 4—

RR of type 2 diabetes according to quintiles of sugar intake in the WHS stratified by BMI

BMI <25 kg/m2
BMI ≥25 kg/m2
Case subjects/person-yearsMultivariate RR∗ (95% CI)Case subjects/person-yearsMultivariate RR∗ (95% CI)
Total sugars
 Q121/20,9421.0189/22,5121.0
 Q225/21,6641.18 (0.65–2014)158/22,0300.91 (0.73–1.13)
 Q320/22,9260.84 (0.44–1.57)156/20,6370.91 (0.73–1.13)
 Q425/24,1240.86 (0.46–1.59)136/19,6760.94 (0.74–1.18)
 Q526/24,8770.86 (0.47–1.58)137/18,6470.88 (0.70–1.11)
P for trendP = 0.36P = 0.38
Sucrose
 Q1 (lowest)25/21,6531.00164/21,8301.00
 Q219/22,3220.69 (0.37–1.29)170/21,0601.10 (0.88–1.35)
 Q317/23,0310.62 (0.33–1.16)157/20,6481.02 (0.82–1.27)
 Q428/23,2300.87 (0.49–1.54)154/20,3881.00 (0.81–1.26)
 Q5 (highest)28/24,2960.77 (0.44–1.36)131/19,5790.87 (0.70–1.12)
P for trendP = 0.70P = 0.25
Fructose
 Q124/20,4931.00178/23,1351.00
 Q216/21,6930.69 (0.36–1.31)167/21,9301.05 (0.84–1.30)
 Q325/23,0971.04 (0.58–1.86)145/20,4231.05 (0.84–1.32)
 Q422/24,1410.83 (0.45–1.0)149/19,4991.09 (0.87–1.36)
 Q530/25,1070.90 (0.51–1.59)137/18,5171.00 (0.79–1.26)
P for trendP = 0.94P = 0.87
Glucose
 Q122/20,5621.00176/23,1421.00
 Q217/21,8780.78 (0.41–1.49)170/21,6961.13 (0.91–1.40)
 Q327/23,0171.15 (0.64–2.05)141/20,5761.00 (0.80–1.26)
 Q420/23,9690.77 (0.41–1.45)143/19,6961.02 (0.81–1.28)
 Q531/25,1051.04 (0.59–1.85)146/18,3941.08 (0.86–1.35)
P for trendP = 0.87P = 0.85
Lactose
 Q131/23,1751.00161/20,5101.00
 Q218/22,7030.63 (0.35–1.13)178/20,8331.17 (0.94–1.45)
 Q327/22,9460.87 (0.51–1.48)154/20,6401.05 (0.83–1.31)
 Q422/22,5860.67 (0.38–1.18)131/21,1720.88 (0.70–1.13)
 Q519/23,1220.60 (0.34–1.08)152/20,3491.06 (0.84–1.33)
P for trendP = 0.13P = 0.57
Starch
 Q125/22,7591.0170/20,6041.0
 Q220/22,5130.75 (0.42–1.37)155/21,3670.96 (0.77–1.20)
 Q320/22,2880.91 (0.50–1.64)174/21,5351.06 (0.85–1.32)
 Q425/22,9321.10 (0.63–1.92)157/20,6651.03 (0.83–1.29)
 Q527/24,0391.03 (0.59–1.81)120/19,3310.85 (0.67–1.08)
P for trendP = 0.54P = 0.98
  • Multivariate RR was adjusted for smoking, BMI, exercise, alcohol use, history of hypertension, high cholesterol, and family history of diabetes.