Table 1—

Patient characteristics and clinical and laboratory data during 20 years of follow-up in 600 patients with type 1 diabetes

Group A (onset from 1965 to 1969)Group B (onset from 1970 to 1974)Group C (onset from 1975 to 1979)Group D (onset from 1979 to 1984)P
n113130113244
Sex (M/F)62/5172/5865/48144/100NS
Age at onset of diabetes (years)*19.8 ± 10.620.9 ± 9.823.1 ± 8.623.2 ± 8.80.003
Smoking (%)69546545<0.001
During follow-up
    HbA1c (%)8.9 ± 0.18.8 ± 0.18.9 ± 0.18.5 ± 0.10.006
    Systolic blood pressure (mmHg)138.1 ± 1.2134.6 ± 1.3131.9 ± 1.3127.9 ± 0.8<0.001
    Diastolic blood pressure (mmHg)84.7 ± 0.782.9 ± 0.781.7 ± 0.779.2 ± 0.5<0.001
    Mean arterial blood pressure (mmHg)102.5 ± 0.8100.1 ± 0.898.4 ± 0.895.4 ± 0.6<0.001
    Class of antihypertensive treatment (ACE inhibitor/non-ACE inhibitor)15/2429/1728/655/6<0.001
    Time from diabetes onset to start of antihypertensive treatment (years)16.9 ± 0.414.8 ± 0.513.9 ± 0.813.3 ± 0.6<0.001
  • Data are

  • *

    * *means ± SD or

  • means ± SE unless otherwise indicated.