Table 5—

Clustering of autoimmune manifestations in four diabetes type 1 families

Family 1Family 2Family 3Family 4
Family members (n)5775
Index caseDB, VIT, HTDB, HTDBDB, HT, CD
FatherNoneNot screenedDBNot screened
MotherCDNoneHTHT
BrotherVITNot screenedPS, CU, JRA
BrotherGADNot screenedNot screened
SisterNot screenedHT
SisterHT, CDDB
SisterHTHT, MG, CD
SisterHT
  • DB, type 1 diabetes; VIT, vitiligo; HT, Hashimoto thyroiditis; CD, celiac disease; PS, psoriasis; CU, chronic urticaria; JRA, juvenile rheumatoid arthritis; MG, myasthenia gravis; GAD, high glutamic acid decarboxylase Ab titer.