Table 2—

History of type 2 diabetes and HRs of invasive breast cancer among 116,488 participants of the Nurses’ Health Study, 1976–1998

No diabetesType 2 diabetes
Breast cancer cases (n)5,403202
Person-years2,306,66459,171
Age-adjusted HR (95% CI)1.001.11 (0.96–1.28)
Covariate-adjusted HR (95% CI)*1.001.17 (1.01–1.35)
  • *

    * Hazard ratios and 95% CI adjusted for age, family history of breast cancer, history of benign breast disease, height, BMI at age 18 years, current BMI, age at menarche, parity, age at first child’s birth, menopausal status, age at menopause, use of postmenopausal hormones, physical activity, and alcohol consumption.