Table 5—

Years since diagnosis of type 2 diabetes and HRs of invasive breast cancer among participants of the Nurses’ Health Study

Years since diagnosis of diabetesBreast cancer cases (n)Person-yearsAge-adjusted HR (95% CI)Covariate-adjusted HR (95% CI)*
No diabetes5,4032,306,6641.001.00
≤5 years8924,6961.22 (0.99–1.51)1.27 (1.02–1.57)
5.1–10 years4815,6451.02 (0.77–1.36)1.09 (0.82–1.46)
10.1–15 years399,5191.31 (0.95–1.80)1.39 (1.01–1.91)
15.1–20 years165,1690.94 (0.58–1.54)1.00 (0.61–1.63)
>20 years104,1540.66 (0.35–1.22)0.69 (0.37–1.29)
P for trend0.690.33
  • *

    * Hazard ratios and 95% CI adjusted for age, family history of breast cancer, history of benign breast disease, height, BMI at age 18 years, current BMI, age at menarche, parity, age at first child’s birth, menopausal status, age at menopause, use of postmenopausal hormones, physical activity, and alcohol consumption.