Table 1—

Clinical characteristics of the study subjects

ParametersNormal subjectsMONW subjects
n2020
Age (years)33.1 ± 1.634.3 ± 1.5
Sex (male/female)19/119/1
BMI (kg/m2)21.0 ± 0.323.5 ± 0.2
Body fat weight (kg)11.8 ± 0.617.1 ± 0.5
Visceral fat area (cm2)57.5 ± 5.5134.4 ± 5.1
Subcutaneous fat area (cm2)97.9 ± 7.4157.5 ± 15.2
Fasting plasma glucose (mmol/l)4.9 ± 0.35.0 ± 0.1
Glucose AUC (mmol/l)749.8 ± 25.0812.1 ± 27.6
Fasting serum insulin (pmol/l)26.4 ± 1.649.8 ± 6.0
Insulin AUC (pmol/l)33,542.7 ± 3,213.146,438.2 ± 5,011.2*
ΔI30/ΔG30124.3 ± 10.8162.7 ± 31.3
Total cholesterol (mmol/l)4.31 ± 0.204.37 ± 0.21
TG (mmol/l)1.05 ± 0.071.89 ± 0.23
HDL cholesterol (mmol/l)1.31 ± 0.061.21 ± 0.04
Serum free fatty acid (mmol/l)0.46 ± 0.050.47 ± 0.04
Systolic blood pressure (mmHg)116.2 ± 2.3127.4 ± 2.2
Diastolic blood pressure (mmHg)71.7 ± 2.180.0 ± 1.3
GIR (μmol · kg−1 · min−1)60.2 ± 2.945.4 ± 1.4
  • Data are means ± SE.

  • *

    * P < 0.05;

  • P < 0.01 vs. normal subjects.