Table 4—

ANCOVA models showing the differences associated with treatment with pioglitazone in CRP, PWV, and adiponectin

Variables with pioglitazone treatmentCovariatesRegression coefficient (SEM)P value
ΔCRPUnadjusted−0.018 (0.010)0.0262
Adjusted for ΔHbA1c−0.041 (0.013)0.0015
 ΔHOMA-IR−0.027 (0.010)0.0117
 ΔBMI−0.042 (0.010)0.0001
ΔPWVUnadjusted−51.94 (21.61)0.0180
Adjusted for ΔHbA1c−50.64 (27.99)0.0423
 ΔHOMA-IR−47.03 (23.31)0.0463
 ΔsBP and ΔdBP−69.49 (26.87)0.0112
 ΔLDL−54.29 (21.89)0.0147
 ΔTriglycerides−49.89 (21.75)0.0238
 ΔCRP−34.56 (23.12)0.1381
 ΔAdiponectin−29.99 (22.47)0.1850
ΔAdiponectinUnadjusted1.808 (0.474)0.0002
Adjusted for ΔHbAA1c1.522 (0.616)0.0151
 ΔHOMA-IR0.547 (0.147)0.0003
  • Changes in variables are indicated by subtracting the pretreatment value from the post-treatment value.