Table 1—

Results of tests of information processing during euglycemia and hyperglycemia in 20 adults with type 2 diabetes

SubtestEuglycemiaHyperglycemiaPFEta2AgeSexGIRHbA1cTAEAHT
Digit Symbol Substitution test70.2 ± 8.466.8 ± 7.80.035.640.240.380.260.650.710.640.570.96
Trail Making B test40.9 ± 7.843.9 ± 8.00.044.770.230.740.770.340.320.380.390.39
Simple Reaction Time test
    Mean359.9 ± 84.6373.7 ± 72.30.102.990.140.810.430.760.330.410.280.08
    SD73.3 ± 11.277.5 ± 17.60.100.470.150.960.180.980.810.500.450.68
    Coefficient of variation21.09 ± 6.8621.82 ± 6.010.380.820.010.920.190.820.650.310.090.16
Four-Choice Reaction Time test
    Mean710.0 ± 116.7775.7 ± 122.9<0.000123.050.560.550.120.480.920.460.760.74
    SD133.1 ± 23.6139.5 ± 41.20.090.680.180.090.480.600.700.670.340.26
    Coefficient of variation18.73 ± 2.7718.22 ± 4.020.640.230.010.060.760.610.680.800.410.95
    Number of errors0.5 ± 0.10.4 ± 0.10.430.540.090.540.650.360.620.510.220.31
  • Data are means ±SD. The effects of age, sex, glucose infusion rate (GIR), HbA1c, and mood as covariates are also shown (all P values). EA, energetic arousal; HT, hedonic tone;TA, tense arousal.