Table 2—

Adjusted* odd ratios (95% CI) of the metabolic syndrome and its components by sex and menopausal-specific quartiles of serum ferritin

Premenopausal women (n = 1,645)Quartile of serum ferritin
≤20 μg/l21–36 μg/l37–60 μg/l>60 μg/lP (trend)
Median ferritin in quartile11264789
Metabolic syndrome1.01.5 (0.7–3.5)2.6 (1.2–5.7)2.4 (1.1–5.2)0.03
Blood pressure ≥130/85 mmHg1.01.3 (0.6–2.6)1.0 (0.4–2.9)0.9 (0.3–2.3)0.37
Plasma glucose ≥6.105 mmol/l1.00.4 (0.2–1.3)0.7 (0.3–2.0)0.8 (0.3–2.4)0.99
HDL cholesterol <1.295 mmol/l1.01.2 (0.7–2.0)1.1 (0.6–2.1)1.2 (0.8–1.8)0.57
Serum triglycerides ≥1.695 mmol/l1.00.8 (0.2–0.9)1.8 (0.5–2.8)1.5 (0.7–2.7)0.07
Waist circumference ≥88 cm1.03.7 (1.3–8.1)1.6 (1.4–6.9)2.8 (1.6–5.9)0.14
Postmenopausal women (n = 1,424)Quartile of serum ferritin
≤54 μg/l55–95 μg/l96–168 μg/l>168 μg/lP (trend)
Median ferritin in quartile3573125212
Metabolic syndrome1.00.8 (0.4–1.3)1.4 (0.7–2.0)2.7 (1.7–4.1)<0.001
Blood pressure ≥130/85 mmHg1.00.4 (0.2–1.0)0.8 (0.3–1.7)1.0 (0.5–2.1)0.21
Plasma glucose ≥6.105 mmol/l1.01.4 (0.8–2.6)2.0 (1.2–3.5)3.6 (2.4–5.5)<0.001
HDL cholesterol <1.295 mmol/l1.00.8 (0.5–1.3)1.1 (0.6–2.0)1.1 (0.7–2.0)0.57
Serum triglycerides ≥1.695 mmol/l1.01.1 (0.7–1.8)2.0 (1.1–3.1)3.2 (1.6–4.6)0.001
Waist circumference ≥88 cm1.00.8 (0.4–1.4)1.5 (0.8–2.5)1.2 (0.5–2.0)0.33
Men (n = 2,880)Quartile of serum ferritin
≤86 μg/l87–145 μg/l146–231 μg/l>231 μg/lP (trend)
Median ferritin in quartile62113182318
Metabolic syndrome1.01.3 (0.8–2.4)1.6 (0.8–3.2)1.6 (0.9–2.7)0.11
Blood pressure ≥130/85 mmHg1.01.2 (0.7–2.0)1.5 (0.8–2.9)1.0 (0.6–1.9)0.89
Plasma glucose ≥6.105 mmol/l 1.01.1 (0.7–1.9)1.5 (0.9–2.5)2.2 (1.4–3.6)0.001
HDL cholesterol <1.036 mmol/l1.00.8 (0.5–1.3)0.9 (0.6–1.4)1.1 (0.7–1.9)0.31
Serum triglycerides ≥1.695 mmol/l1.01.6 (1.0–2.6)1.7 (1.0–2.6)2.7 (1.6–4.6)0.004
Waist circumference ≥102 cm1.01.2 (0.5–2.9)1.5 (0.8–2.8)0.8 (0.5–1.3)0.27
  • *

    * Adjusted for age, race/ethnicity, CRP, smoking, alcohol intake, and BMI.

  • Includes individuals who reported current use of antihypertensive medications regardless of blood pressure values.

  • Includes individuals who reported current use of oral hypoglycemic medications or insulin regardless of fasting glucose values.