Table 3—

Geometric mean (95% CI) values of estimated insulin resistance by sex and menopausal-specific quartiles of serum ferritin in nondiabetic U.S. adults

Premenopausal women (n = 1,612)Quartile of serum ferritin
≤20 μg/l21–36 μg/l37–60 μg/l>60 μg/lP (trend)
Median ferritin in quartile11264789
HOMA-IR1.9 (1.7–2.1)1.7 (1.6–1.8)1.9 (1.8–2.1)1.9 (1.8–2.2)0.14
Fasting insulin (pmol/l)49.9 (46.0–54.1)45.8 (42.6–49.8)52.4 (48.8–56.3)51.8 (47.3–56.7)0.16
Triglyceride-to-HDL ratio0.71 (0.62–0.81)0.72 (0.66–0.80)0.75 (0.67–0.83)0.82 (0.73–0.92)0.06
Postmenopausal women (n = 1,234)Quartile of serum ferritin
≤54 μg/l55–95 μg/l96–168 μg/l>168 μg/lP (trend)
Median ferritin in quartile3573125212
HOMA-IR2.0 (1.9–2.2)1.9 (1.7–2.1)2.3 (2.2–2.6)2.5 (2.3–2.8)<0.001
Fasting insulin (pmol/l)51.3 (47.8–55.1)49.0 (44.9–53.5)58.0 (54.2–62.2)62.3 (57.0–68.2)<0.001
Triglyceride-to-HDL ratio1.03 (0.92–1.16)0.87 (0.79–0.96)1.07 (0.98–1.16)1.28 (1.11–1.48)0.001
Men (n = 2,618)Quartile of serum ferritin
≤86 μg/l87–145 μg/l146–231 μg/l>231 μg/lP (trend)
Median ferritin in quartile62113182318
HOMA-IR1.9 (1.7–2.0)2.0 (1.9–2.2)2.1 (2.0–2.3)2.5 (2.3–2.6)<0.001
Fasting insulin (pmol/l)47.8 (44.2–51.6)51.8 (48.3–55.6)52.8 (49.1–56.8)60.2 (56.9–63.7)<0.001
Triglyceride-to-HDL ratio1.05 (0.95–1.17)1.11 (0.99–1.26)1.21 (1.11–1.33)1.41 (1.28–1.62)<0.001
  • Data are means (95% CI).