Table 4—

Multivariate ORs for key risk factors associated with amputation in diabetes

OR (95% CI)P
Minor amputation
    High-risk footwear2.52 (1.07–5.92)0.03
    Daily foot self-examination0.28 (0.12–0.63)0.002
    GHb level (per % increase)1.35 (1.20–1.52)<0.001
    ABI (per unit increase)0.27 (0.10–0.74)0.01
    VPT (per unit volt increase)1.06 (1.03–1.09)<0.001
Major amputation
    High-risk footwear3.85 (0.93–15.95)0.06
    Daily foot self-examination0.09 (0.03–0.31)<0.001
    GHb level (per % increase)1.51 (1.28–1.79)<0.001
    ABI (per unit increase)0.15 (0.03–0.71)0.02
    VPT (per unit volt increase)1.04 (0.99–1.08)0.08
All amputations
    High-risk footwear2.71 (1.23–5.97)0.03
    Daily foot self-examination0.20 (0.10–0.42)0.002
    GHb level (per % increase)1.40 (1.26–1.57)<0.001
    ABI (per unit increase)0.25 (0.10–0.66)0.01
    VPT (per unit volt increase)1.05 (1.03–1.08)<0.001
  • ABI, ankle brachial index; VPT, vibration perception threshold.