Table 1—

Characteristics of study participants by HOMA-IR quartile

VariableHOMA-IR quartile
P for trend
<1.401.40–1.981.99–2.85≥2.86
Age (years)41.1 ± 0.743.8 ± 0.845.3 ± 0.748.5 ± 0.6<0.001
Male (%)44.9 ± 2.147.5 ± 2.254.4 ± 2.253.2 ± 1.80.432
Ethnicity (% African American)8.1 ± 0.89.7 ± 0.710.1 ± 0.811.8 ± 0.9<0.001
Hispanic (%)4.1 ± 0.54.0 ± 0.44.6 ± 0.67.4 ± 0.7<0.001
High school education (%)80.5 ± 1.478.0 ± 1.776.2 ± 2.270.7 ± 1.8<0.001
Physically inactive (%)31.5 ± 1.834.6 ± 2.237.8 ± 1.948.9 ± 1.9<0.001
Current smoker (%)35.9 ± 2.528.5 ± 1.724.9 ± 1.622.8 ± 1.9<0.001
Former smoker (%)20.2 ± 1.822.5 ± 1.729.1 ± 1.724.7 ± 2.1<0.001
Alcohol drinker (%)65.6 ± 2.457.7 ± 2.458.8 ± 1.443.3 ± 2.2<0.001
NSAID use in the past month (%)77.5 ± 1.578.9 ± 1.677.6 ± 1.578.6 ± 1.30.251
BMI (kg/m2)22.6 ± 0.124.6 ± 0.126.7 ± 0.231.2 ± 0.3<0.001
Waist circumference (cm)80.9 ± 0.486.9 ± 0.493.5 ± 0.5104.2 ± 0.6<0.001
Systolic blood pressure (mmHg)116.2 ± 0.6119.3 ± 0.7123.6 ± 0.7127.6 ± 0.6<0.001
Diastolic blood pressure (mmHg)70.9 ± 0.472.3 ± 0.475.1 ± 0.478.2 ± 0.4<0.001
Total cholesterol (mg/dl)189.8 ± 1.7202.4 ± 1.5208.3 ± 1.5214.5 ± 1.3<0.001
Triglycerides (mg/dl)89.5 ± 2.3114.5 ± 3.2137.8 ± 3.1182.7 ± 4.3<0.001
GFR (ml · min−1 · 1.73 m−2)118.2 ± 1.4113.3 ± 1.5110.8 ± 1.2107.0 ± 1.4<0.001
Ferritin (ng/ml)104.4 ± 3.9110.5 ± 4.5136.1 ± 6.6153.4 ± 4.6<0.001
Uric acid (mg/dl)4.9 ± 0.065.1 ± 0.065.4 ± 0.056.1 ± 0.07<0.001
White blood cell count (×109/l)6.4 ± 0.16.5 ± 0.16.7 ± 0.17.3 ± 0.1<0.001
Fibrinogen (mg/dl)285.9 ± 5.4305.9 ± 4.1302.1 ± 4.3319.5 ± 3.9<0.001
C-reactive protein (% detectable [0.22–0.99 mg/dl])10.5 ± 1.415.3 ± 1.321.5 ± 2.331.1 ± 2.3<0.001
Clinically elevated (≥1.0 mg/dl)2.7 ± 0.65.3 ± 0.73.9 ± 0.612.1 ± 1.2<0.001
  • Data are means ± SE.