Table 2—

Unadjusted, univariate, and multivariate linear regression analysis of inflammatory markers on HOMA-IR

Variable (1 SD)Unadjusted
Age, sex, and race adjusted
Multivariate adjusted*
β95% CIPβ95% CIPβ95% CIP
Ferritin (126.1 ng/ml)0.260.19–0.33<0.0010.230.16–0.30<0.0010.100.03–0.170.004
Uric acid (1.4 mg/dl)0.540.44–0.63<0.0010.640.53–0.76<0.0010.160.08–0.24<0.001
White blood cell count (2.2 × 109/l)0.300.21–0.39<0.0010.300.21–0.38<0.0010.160.09–0.22<0.001
Fibrinogen (80.6 mg/dl)0.250.17–0.34<0.0010.260.17–0.34<0.0010.120.05–0.180.001
Detectable C-reactive protein0.750.59–0.91<0.0010.720.58–0.87<0.0010.02−0.12 to 0.170.745
Clinically elevated1.480.97–1.99<0.0011.450.92–1.97<0.0010.630.23–1.040.003
  • *

    * Adjusted for age, sex, race, education, physical activity, current and former smoking, alcohol intake, NSAID use in the past month, systolic blood pressure, BMI, waist circumference, serum total cholesterol, and triglycerides.

  • Detectable C-reactive protein level: 0.22–0.99 mg/dl; clinically elevated C-reactive protein level: ≥1.0 mg/dl.