Table 2—

Results after 2 and 3 months of treatment

VariableCaiapo
Placebo
Baseline2 months3 monthsBaseline2 months3 months
Fasting blood glucose (mg/dl)143.7 ± 1.9132.3 ± 1.8*128.5 ± 1.7*144.3 ± 1.9138.8 ± 2.2138.2 ± 2.1
Glucose 2 h after OGTT (mg/dl)193.3 ± 10.4164.9 ± 6.9*162.8 ± 8.2*191.7 ± 9.2187.5 ± 7.3181.0 ± 7.1
Glucose 2 h after lunch (mg/dl)169.5 ± 4.5156.5 ± 4.0*150.6 ± 2.6*167.1 ± 6.2156.6 ± 3.8157.8 ± 4.0
Glucose 2 h after dinner (mg/dl)172.9 ± 5.1159.9 ± 3.2*155.0 ± 3.0*163.5 ± 4.2158.5 ± 3.8155.0 ± 3.7
HbA1c (%)7.21 ± 0.156.94 ± 0.14*6.68 ± 0.14*7.04 ± 0.177.05 ± 0.197.10 ± 0.19
Body weight (kg)78.9 ± 1.775.8 ± 1.4§75.2 ± 1.4§77.2 ± 2.076.1 ± 1.876.2 ± 1.7
Total cholesterol (mg/dl)225.1 ± 10.1NA214.6 ± 11.2240.9 ± 10.4NA248.7 ± 11.2
Triglycerides (mg/dl)211.6 ± 14.3NA205.4 ± 17.0216.1 ± 15.2NA219.7 ± 15.2
  • Data are means ± SE.

  • *

    * P < 0.001,

  • P < 0.05,

  • P < 0.01,

  • §

    § P < 0.0001,

  • P < 0.03,

  • P < 0.003; all versus baseline. NA, not assessed.