Table 3—

RH of type 2 diabetes over 6 years of follow-up by vital exhaustion depression subscore among 11,615 individuals age 48–67 years

Vital exhaustion depression subscore category*Age, race, ARIC center, education, and sex adjusted hazard ratio (95% CI)Fully adjusted model (95% CI)
Vegetative score1.22 (1.11–1.36)§1.10 (0.99–1.23)
Nonvegetative score1.20 (1.09–1.32)§1.09 (0.98–1.20)
Functional score1.23 (1.11–1.36)§1.11 (1.00–1.23)§
  • *

    * Vegetative symptoms (fatigue, sleep pattern, energy, concentration); nonvegetative symptoms (crying spells, hopelessness, irritability, enjoyment of sex, suicidality); functional symptoms (coping, productivity).

  • Risk of incident type 2 diabetes per interquartile range increase in vital exhaustion depression subscore category (each hazard ratio has been standardized to the interquartile range for the distribution of its scores).

  • Adjusted for age, race, ARIC center, education, sex, fasting insulin, fasting glucose, log triglycerides, HDL cholesterol, BMI, waist-to-hip ratio, systolic blood pressure, physical activity, total caloric intake, and smoking status.

  • §

    § P < 0.05.