Table 1—

Baseline characteristics of the three different cohorts: the first half of the Inter99 study, the second half of the Inter99 study, and the ADDITION pilot study

Inter99 first halfInter99 second halfADDITION pilot study
n3,2502,8741,028
% IGT12.6 (409)10.9 (313)9.2 (95)
% SDM4.2 (135)4.1 (117)2.8 (29)
% Men49.8 (48.1–51.5)49.3 (47.5–51.2)6.0 (42.9–49.1)
Age (years)46.0 ± 7.946.0 ± 7.850.7 ± 7.8
BMI (kg/m2)26.2 ± 4.426.3 ± 4.625.1 ± 3.9
% BMI 25.0–29.9 kg/m239.5 (37.8–41.2)39.6 (37.8–41.4)33.8 (30.9–36.8)
% BMI 30 kg/m216.3 (15.1–17.7)16.5 (15.2–17.9)10.9 (9.1–13.0)
HbA1c (%)5.8 ± 0.55.8 ± 0.55.6 ± 0.5
% Known hypertension18.6 (17.3–20.0)17.6 (16.2–19.0)19.3 (16.9–21.8)
Systolic blood pressure (mmHg)129 ± 17131 ± 17142 ± 18§
Diastolic blood pressure (mmHg)81 ± 1184 ± 1184 ± 11§
Total cholesterol (mmol/l)5.5 ± 1.15.5 ± 1.15.8 ± 1.0§
% Parent having diabetes*15.1 (13.9–16.3)13.7 (12.5–15.0)17.1 (14.8–19.5)
% Sibling having diabetes*4.4 (3.7–5.2)4.0 (3.3–4.8)
% Physical inactive and moderate active82.0 (80.7–83.3)83.9 (82.5–85.2)78.0 (75.4–80.5)
% Daily smoker36.8 (35.1–38.5)34.5 (32.8–36.3)31.0 (28.3–34.1)
  • Data are means ± SD or, where stated, percentages (95% CI). For % IGT and % SDM, values are percentages (n). Comparison of baseline characteristics between the population in which the algorithm was derived (first half of the Inter99 population) and the populations (the second half of the Inter99 population cohort and the ADDITION pilot study).

  • *

    * In the ADDITION pilot study only information on family history of diabetes (either parents or siblings) was available;

  • P < 0.05;

  • P < 0.01;

  • §

    § P < 0.001.