Table 2—

HRR for all-cause mortality associated with weight change and with degree of weight loss or gain among overweight and obese persons with diabetes

Weight change (median)Prevalence (%)Death rate (%/year)Primary model* HRR (95% CI)Fully adjusted HRR (95% CI)
No weight change045.63.01.01.0
Weight loss (lb)−1545.54.01.22 (0.99–1.50)1.19 (0.96–1.47)
 1–19−1026.43.61.11 (0.87–1.41)1.09 (0.85–1.40)
 ≥20−3019.14.61.40 (1.05–1.87)1.36 (1.03–1.80)
Weight gain (lb)108.93.61.11 (0.74–1.66)1.10 (0.72–1.67)
 1–1986.83.00.97 (0.62–1.53)1.00 (0.61–1.63)
 ≥20252.25.41.77 (0.97–3.23)1.48 (0.82–2.68)
  • *

    * Primary model adjusted for age, sex, race, smoking, education, and initial BMI;

  • fully adjusted model: initial BMI, age, race, sex, education, self-rated health, smoking, diabetes medications, duration of disease, functional limitations, hypertension, heart disease, stroke, retinal disease, neuropathy symptoms, hospital days, and doctor visits.