Unadjusted and adjusted predictors for incident metabolic syndrome per SD
Variable (SD) | Unadjusted | Adjusted* | Adjusted for IGT† |
---|---|---|---|
Age (8.5 years) | 0.9 (0.8–1.1) | — | — |
Sex | 0.8 (0.6–1.2) | — | — |
Study site | |||
Los Angeles | 0.8 (0.5–1.4) | — | — |
Oakland | 1.3 (0.8–2.2) | — | — |
San Antonio | 1.3 (0.8–2.2) | — | — |
Ethnicity | |||
Black | 0.8 (0.5–1.3) | — | — |
Hispanic | 1.0 (0.6–1.5) | — | — |
Metabolic syndrome components | |||
Waist circumference (11.0 cm) | 1.5 (1.3–1.9) | 1.8 (1.4–2.2) | 1.7 (1.3–2.0) |
Triglycerides (70.5 mg/dl) | 1.3 (1.1–1.5) | 1.3 (1.1–1.6) | 1.3 (1.1–1.5) |
HDL cholesterol (15.3 mg/dl) | 0.7 (0.5–0.8) | 0.6 (0.4–0.7) | 0.6 (0.4–0.7) |
Systolic blood pressure (16.0 mmHg) | 1.2 (1.0–1.4) | 1.3 (1.0–1.6) | 1.3 (1.0–1.6) |
Diastolic blood pressure (9.0 mmHg) | 1.1 (0.9–1.3) | 1.2 (1.0–1.4) | 1.1 (0.9–1.4) |
Fasting glucose (10.4 mg/dl) | 1.4 (1.2–1.7) | 1.5 (1.2–1.8) | 1.3 (1.1–1.6) |
Fasting insulin (15.4 μU/ml) | 1.3 (1.1–1.6) | 1.3 (1.1–1.6) | 1.2 (1.0–1.5) |
Proinsulin (3.3 pmol/l) | 1.7 (1.4–2.0) | 1.8 (1.5–2.2) | 1.7 (1.4–2.0) |
Insulin sensitivity (Si) (2.1 · 10−4 · min−1 · μU−1 · ml−1) | 0.6 (0.5–0.8) | 0.5 (0.4–0.7) | 0.6 (0.5–0.8) |
Acute insulin response (471.4 pmol · ml−1 · min−1) | 0.9 (0.8–1.1) | 1.0 (0.8–1.2) | 1.0 (0.8–1.3) |
2-h insulin (72.9 μU/ml) | 1.3 (1.1–1.6) | 1.4 (1.2–1.6) | 1.0 (0.8–1.3) |
2-h glucose (32.1 mg/dl) | 1.5 (1.2–1.8) | 1.6 (1.3–1.9) | 1.2 (0.8–1.6) |
Total energy expenditure (2,709 kcal · kg−1 · year−1) | 1.0 (0.8–1.2) | 1.0 (0.8–1.2) | 1.0 (0.8–1.2) |
IGT (yes/no) | 2.6 (1.8–3.8) | 3.0 (2.0–4.4) | — |