Table 3—

Multivariate baseline predictors of risk for renal end points in the RENAAL study Asian population

Renal eventBaseline risk factorHazard ratio95% CI
P value
UpperLower
Cox proportional hazards model using prespecified covariates*
 Primary compositeProteinuria/1,000 mg1.391.281.51<0.0001
Hemoglobin0.820.740.91<0.0001
 DsCr or ESRDProteinuria/1,000 mg1.421.301.55<0.0001
Hemoglobin0.810.720.91<0.0001
 ESRD aloneProteinuria/1,000 mg1.241.391.11<0.0001
Calcium0.340.630.180.001
Age/10 years0.540.790.540.002
Hb0.790.940.670.006
Serum creatinine2.254.181.220.010
  • *

    * Prespecified covariates selected are as follows: age, sex, BMI, smoking, insulin use, systolic blood pressure, diastolic blood pressure, serum creatinine, estimated glomerular filtration rate, proteinuria, serum albumin, total cholesterol, lipoprotein(a), serum triglycerides, serum calcium, Hb, serum uric acid, GHb, white blood cell count, and dihydropyridine calcium channel blocker use.