Table 1—

Definitions of the metabolic syndrome

ATP III metabolic syndrome definition
 At least three of the following criteria
  Waist circumference >102 cm in men and >88 cm in women
  Serum triglycerides ≥150 mg/dl
  HDL cholesterol <40 mg/dl in men and <50 mg/dl in women
  Blood pressure ≥130/85 mmHg
  Serum glucose ≥110 mg/dl
WHO metabolic syndrome definition
 Diabetes, IFG, IGT, or HOMA insulin resistant and at least two of the following criteria
  Waist-to-hip ratio >0.90 in men or >0.85 in women
  Serum triglycerides ≥150 mg/dl or HDL cholesterol <35 mg/dl in men and <39 mg/dl in women
  Urinary albumin excretion rate >20 μg/min
  Blood pressure≥140/90 mm/Hg
AACE IRS definition
 Presence of at least one of the following factors
  Diagnosis of CVD, hypertension, PCOS, NAFLD, or acanthosis nigricans
  Family history of type 2 diabetes, hypertension, or CVD
  History of gestational diabetes or glucose intolerance
  Non-Caucasian ethnicity
  Sedentary lifestyle
  BMI >125.0 kg/m2 and/or waist circumference >40 in in men and >35 in in women
  Age >40 years
and at least two of the following criteria
  Triglycerides >150 mg/dl
  HDL cholesterol <40 mg/dl in men and <50 mg/dl in women
  Blood pressure >130/85 mmHg
  Fasting glucose 110-125 mg/dl or 120-min postglucose challenge 140-200 mg/dl (diabetes is excluded from the AACE IRS)
EGIR IRS definition
 Fasting hyperinsulinemia (highest 25%) and at least two of the following criteria
  Fasting plasma glucose ≥6.1 mmol/l (excluding diabetes)
  Blood pressure ≥140/90 mmHg or treated for hypertension
  Triglycerides >2.0 mmol/l or HDL cholesterol <1.0 mmol/l or treated for dyslipidemia
  Waist circumference ≥94 cm in men and ≥80 cm in women