Table 1

Baseline (at time of CVD event) patient characteristics stratified by CVD (MI and stroke) and prior hypoglycemic events in our sample

Missing in overall (%)OverallMIStrokeNo prior hypoglycemic eventPrior hypoglycemic event
n in sample1,8391,2246151,436403
Age at event (years)*059.46 (11.76)60.27 (11.58)57.84 (11.95)59.13 (11.49)60.64 (12.61)
Diabetes duration (years)*044.25 (12.45)45.24 (12.22)42.30 (12.68)43.86 (12.38)45.68 (12.62)
HbA1c (%)0.498.27 (1.27)8.26 (1.26)8.28 (1.28)8.28 (1.24)8.23 (1.36)
HbA1c (mmol/mol)0.4966.89 (13.87)66.81 (13.79)67.06 (14.03)67.00 (13.56)66.50 (14.89)
BMI (kg/m2)*4.3525.72 (4.31)25.93 (4.32)25.32 (4.28)25.97 (4.30)24.85 (4.23)
Total–to–HDL cholesterol ratio14.143.39 (1.22)3.44 (1.26)3.29 (1.12)3.41 (1.25)3.32 (1.12)
HDL (mmol/L)13.971.57 (0.50)1.55 (0.50)1.61 (0.50)1.57 (0.50)1.58 (0.50)
LDL (mmol/L)13.872.72 (0.92)2.73 (0.91)2.71 (0.94)2.73 (0.93)2.70 (0.91)
Triglycerides (mmol/L)12.291.41 (0.90)1.43 (0.96)1.35 (0.78)1.41 (0.91)1.39 (0.89)
Systolic blood pressure (mmHg)0.76139.07 (19.99)138.32 (19.75)140.57 (20.37)139.44 (19.68)137.77 (21.01)
Diastolic blood pressure (mmHg)0.7672.60 (10.57)71.47 (10.43)74.84 (10.48)72.63 (10.51)72.47 (10.78)
eGFR (mL/min/1.73 m2)7.1865.97 (29.69)64.75 (29.44)68.43 (30.06)66.17 (29.29)65.26 (31.08)
Sex (male = 1), n (%)*01,015 (55)644 (53)371 (60)775 (54)240 (60)
Lipid medication, n (%)8.211,080 (58)745 (61)335 (55)852 (54)228 (63)
Smoking, n (%)1.25275 (15)182 (15)93 (15)217 (15)58 (15)
Microalbuminuria, n (%)0944 (51)630 (51)314 (51)732 (51)212 (53)
Macroalbuminuria, n (%)0526 (29)345 (28)181 (29)411 (29)115 (29)
Prior MI, n (%)0289 (16)230 (19)59 (10)218 (15)71 (18)
Prior stroke, n (%)*0180 (10)94 (8)86 (14)128 (9)52 (13)
Prior heart failure, n (%)0227 (12)177 (14)50 (8)176 (12)51 (13)
Prior hyperglycemia, n (%)*0264 (14)157 (13)107 (17)183 (13)81 (20)
Prior PVD, n (%)*0496 (27)344 (28)152 (25)358 (25)138 (34)
Prior amputation, n (%)*0109 (6)71 (6)38 (6)74 (5)35 (9)
Prior ESRD, n (%)*0176 (10)106 (9)70 (11)122 (8)54 (13)
Prior unstable angina/IHD, n (%)0629 (34)478 (39)151 (25)481 (33)148 (37)
Prior AF, n (%)075 (4)53 (4)22 (4)55 (4)20 (5)
Prior PCI, n (%)0164 (9)131 (11)33 (5)126 (9)38 (9)
Prior CABG, n (%)0280 (15)210 (17)70 (11)215 (15)65 (16)
  • Data are means (SD) unless otherwise indicated.

  • *With use of the Mann-Whitney test, variables are statistically significant at the 5% level for differences between patients with no prior hypoglycemic event versus patients with a prior hypoglycemic event.