Table 3—

Summary of quantitative sensory changes from baseline at 12 months in placebo patients*

MeasureBaselineChange from baselineP (95% CI)
Cool thermal471360
14.16 ± 4.520.60 ± 3.250.0005 (0.27 to 0.94)
 HbA1c ≤8%275217
14.0 ± 4.40.4 ± 3.40.0844 (−0.05 to 0.85)
 HbA1c >8%170121
14.4 ± 4.71 ± 3.10.0007 (0.42 to 1.54)
Vibratory471359
19.31 ± 3.210.07 ± 1.700.4692 (−0.11 to 0.24)
 HbA1c ≤8%275216
19.5 ± 3.1−0.02 ± 1.60.8424 (−0.24 to 0.20)
 HbA1c >8%170121
19 ± 3.40.3 ± 1.80.1069 (−0.06 to 1.54)
  • Data are means ± SD.

  • *

    * No response values had a value imputed. See text for details.

  • None of the change from baseline comparisons between HbA1c strata are statistically different at P < 0.05.

  • Baseline data are in “just noticeable difference” units.