Table 2—

Body weight and FPG and plasma lipid levels before and after diet therapy in type 2 diabetic patients with the apoE3/3 or the apoE4/3 genotype

ApoE3/3 genotype
ApoE4/3 genotype
BeforeAfterP*BeforeAfterP*
Body weight (kg)64.3 ± 3.061.9 ± 2.6NS65.1 ± 1.963.1 ± 5.2NS
FPG (mg/dl)185 ± 33122 ± 20<0.001182 ± 17135 ± 17<0.001
Total cholesterol (mg/dl)224 ± 8207 ± 7NS235 ± 10195 ± 8<0.05
LDL cholesterol (mg/dl)134 ± 2133 ± 3NS147 ± 3†125 ± 2‡<0.001
HDL cholesterol (mg/dl)50 ± 347 ± 2NS43 ± 340 ± 2NS
Triglyceride (mg/dl)199 ± 20136 ± 12<0.05224 ± 25153 ± 15<0.05

  • Data are means ± SE.

  • *

    ↵* P values before vs. after diet therapy;

  • †

    ↵† P < 0.01 vs. before diet therapy in patients with the apoE3/3 genotype;

  • ‡

    ↵‡ P < 0.05 vs. after diet therapy in patients with the apoE3/3 genotype.