Table 1—

Three classification systems for DNs

A: Clinical Classification of DNs
PolyneuropathyMononeuropathy
SensoryIsolated peripheral
 • Acute sensory
 • Chronic sensorimotorMononeuritis multiplex
Autonomic
 • CardiovascularIsolated peripheral
 • Gastrointestinal
 • GenitourinaryTruncal
 • Other
Proximal motor (amyotrophy)
Truncal
Adapted from Boulton and Ward (22) and Boulton and Malik (11).
B: Patterns of Neuropathy in Diabetes
Length-dependent diabetic polyneuropathy
• Distal symmetrical sensory polyneuropathy
• Large fiber neuropathy
• Painful symmetrical polyneuropathy
• Autonomic neuropathies
Focal and multifocal neuropathies
• Cranial neuropathies
• Limb neuropathies
• Proximal DN of the lower limbs
• Truncal neuropathies
Nondiabetic neuropathies more common in diabetes
• Pressure palsies
• Acquired inflammatory demyelinating polyneuropathy
Adapted from Said (25).
C: Classification of DN
Rapidly reversible
• Hyperglycemic neuropathy
Generalized symmetrical polyneuropathies
• Sensorimotor (chronic)
• Acute sensory
• Autonomic
Focal and multifocal neuropathies
• Cranial
• Thoracolumbar radiculoneuropathy
• Focal limb
• Proximal motor (amyotrophy)
Superimposed chronic inflammatory demyelinating neuropathy
Adapted from Thomas (23,24).