Sociodemographic, clinical, bacteriologic, and therapeutic characteristics of patients with pulmonary tuberculosis according to diagnosis of diabetes, Orizaba, Veracruz, 1995–2003
| Total population | Diabetic patients | Nondiabetic patients | P* | |
|---|---|---|---|---|
| n | 581 | 172 | 409 | |
| Sociodemographic | ||||
| Household visit to invite participation | 32 | 23.5 | 35.6 | <0.0001 |
| Age (years) | 44 (19–86) | 53 (23–82) | 39 (19–86) | <0.0001 |
| Men | 59.9 | 55.2 | 61.9 | 0.1 |
| Indigenous origin | 23.2 | 18.0 | 25.4 | 0.05 |
| Rural and industrial workers | 22.9 | 15.7 | 25.9 | 0.007 |
| Bacille Calmette-Guérin scar | 44.2 | 30.8 | 49.9 | <0.0001 |
| Previous hospitalization | 50.4 | 62.8 | 45.2 | <0.0001 |
| Residence in shelters | 3.8 | 0.0 | 5.4 | 0.002 |
| Social security | 34.9 | 51.7 | 27.9 | <0.0001 |
| Alcohol use | 47.7 | 40.7 | 50.6 | 0.02 |
| Household crowding | 36.3 | 28.1 | 39.0 | 0.01 |
| Household with earthen floor | 19.7 | 11.9 | 23.0 | 0.002 |
| Clinical | ||||
| HIV infection | 2.7 | 1.2 | 3.3 | 0.2 |
| BMI (<18 kg/m2) | 22.8 | 8.1 | 28.9 | <0.0001 |
| Hemoptysis | 32.9 | 34.5 | 32.3 | 0.6 |
| Fever | 75.9 | 77.9 | 75.1 | 0.5 |
| Cavities | 35.8 | 42.8 | 32.9 | 0.02 |
| Interval between initiation of symptoms and treatment (days) | 104 (3–3,248) | 99 (4–1,569) | 109 (3–3,248) | 0.8 |
| Bacteriologic | ||||
| Resistance to isoniazid and rifampin | 5.7 | 8.1 | 4.7 | 0.1 |
| Other resistance | 14.5 | 14.0 | 14.7 | 0.8 |
| Treatment outcome | ||||
| Cure | 82.7 | 82.4 | 82.9 | 0.9 |
| Failure | 2.5 | 4.8 | 1.5 | 0.02 |
| Default | 9.9 | 9.1 | 10.2 | 0.7 |
| Retreatment | 7.0 | 9.3 | 6.1 | 0.2 |
| All-cause mortality | 16.4 | 19.8 | 14.9 | 0.1 |
| Death from tuberculosis | 7.9 | 5.8 | 8.8 | 0.2 |
| Death from other causes | 8.4 | 14.0 | 2.4 | 0.001 |
Data are % or median (range).
↵* For comparison between diabetic and nondiabetic patients; χ2 and Wilcoxon’s tests were used.