Table 3—

Metabolic characteristics of postmenopausal women before and after weight loss (n = 37)

BeforeAfter
Age (years)57 ± 1
Weight (kg)86.4 ± 2.380.3 ± 2.2*
Body fat (%)46.8 ± 0.843.5 ± 0.8*
Fat mass (kg)40.2 ± 1.634.9 ± 1.5*
FFM (kg)45.0 ± 1.144.2 ± 0.9
VAT (cm2)147.8 ± 8.4121.6 ± 7.2*
SAT (cm2)470.0 ± 19.4399.9 ± 17.8*
Vo2max (l/min)1.73 ± 0.061.74 ± 0.06
Plasma glucose (mmol/l)5.2 ± 0.14.9 ± 0.1*
Plasma insulin (pmol/l)54 ± 348 ± 2*
Glucose utilization
 μmol · kg−1 · min−126.3 ± 1.331.0 ± 1.4*
 μmol · kgFFM−1 · min−152.4 ± 2.456.0 ± 2.4
Insulin sensitivity
 μmol · kg−1 · min−1/pmol/l0.058 ± 0.0030.069 ± 0.003
 μmol · kgFFM−1 · min−1/pmol/l0.112 ± 0.0060.124 ± 0.006
CRP (μg/ml)5.7 ± 0.65.3 ± 1.0
TNF-α (pg/ml)2.25 ± 0.502.44 ± 0.55
sTNFR-1 (pg/ml)776 ± 33728 ± 30
sTNFR-2 (pg/ml)1,842 ± 721,801 ± 68
IL-6 (pg/ml)1.89 ± 0.121.59 ± 0.13
IL-6sR (pg/ml)23,225 ± 99722,857 ± 867
  • Data are means ± SEM. Significantly different before vs. after weight loss:

  • *

    * P < 0.001;

  • P < 0.05;

  • P < 0.01.