Risk of IHD events among nondiabetic subjects in the NHS92 according to glucose tolerance stratified by both FPG and 2-h PG after a 75-g OGTT
| Glucose tolerance based on FPG criteria | n | Person-years | Hazard ratio (95% CI) | ||
|---|---|---|---|---|---|
| Total | Cases | ||||
| Analyses with subjects pooled within categories of FPG if FPG 5.6–6.9 mmol/l | |||||
| FPG <5.6 mmol/l | |||||
| NGT* | — | 14 | 13,633.7 | 1 | |
| IGT* | — | 8 | 1,226.9 | 3.00 (1.22–7.38) | |
| FPG 5.6–6.0 mmol/l | — | 12 | 3,463.6 | 1.42 (0.65–3.14) | |
| FPG 6.1–6.9 mmol/l | — | 6 | 1,096.1 | 1.60 (0.60–3.14) | |
| Analyses with study subjects stratified by both FPG and 2-h PG criteria | |||||
| FPG <5.6 mmol/l | |||||
| NGT* | 2,137 | 14 | 13,633.7 | 1 | |
| IGT* | 289 | 8 | 1,226.9 | 3.07 (1.26–7.56) | |
| FPG 5.6–6.0 mmol/l | |||||
| NGT* | 388 | 4 | 2,458.9 | 0.69 (0.22–2.12) | |
| IGT* | 154 | 8 | 1,004.4 | 3.08 (1.26–7.52) | |
| FPG 6.1–6.9 mmol/l | |||||
| NGT* | 85 | 2 | 540.5 | 1.09 (0.24–4.90) | |
| IGT* | 86 | 4 | 555.6 | 2.09 (0.67–6.49) | |
Hazard ratios were estimated using Cox proportional hazards models and adjusted for age, sex, and ethnic group.
↵* Glucose tolerance based on 2-h PG criteria.