Table 1—

Hemoglobin nomenclature

HbAThe major form of hemoglobin, a native, unmodified tetramer consisting of two α-chains and two β-chains
GHbA general term for glucose bound nonenzymatically to hemoglobin and with a ketoamine structure.
HbA1GHb species that are more negatively charged forms of HbA detected by cation-exchange chromatographic and electrophoretic methods, which include HbA1a, HbA1b, and HbA1c; also called the “fast” hemoglobins
HbA1cA specific GHb that is an adduct of glucose attached to the β-chain terminal valine residue
Total GHbA term used to describe all GHb species as measured by affinity chromatographic methods.