Table 3

Change in depressive symptoms over 12 months for trial and nonscreened usual care control patients

Baseline 12 months Change*P value**
Mean (SD)Mean (SD)Mean (SD)
PHQ score
 Intervention (n = 95)14.5 (3.8)7.1 (5.4)−7.3 (5.6)<0.001
 Active control (n = 62)14.6 (3.5)9.4 (5.9)−5.2 (5.7)0.030
 Usual care control (n = 71)14.2 (3.4)11.0 (5.2)−3.2 (4.9)
NNT***P value**
%n
Proportion recovered (PHQ improved by 50%)
 Intervention (n = 95)613<0.001
 Active control (n = 62)4450.034
 Usual care control (n = 71)24
Proportion achieving amelioration (PHQ <10)
 Intervention (n = 95)683<0.001
 Active control (n = 62)5850.020
 Usual care control (n = 71)39
  • NNT, number needed to treat.

  • *Change from baseline to 12 months.

  • **From linear (PHQ score change) or logistic (proportions) regressions comparing with usual care control subjects, after adjusting for age.

  • ***NNT over 12 months to achieve amelioration compared with usual care control subjects.