Table 2—

Prevalences and means, adjusted by age, of CVD risk factors, metabolic syndrome, and insulin sensitivity and secretion indexes

NGTIsolated IFGIsolated IGTIFG/IGTPHomogeneity groups
n6631325948
A1C (%)4.88 (4.85–4.91)4.99 (4.92–5.05)4.95 (4.85–5.04)5.29 (5.18–5.39)<0.001{1,3} {2,3} {4}
Hypertension (%)30.134.539.655.4<0.001{1,2,3} {4}
Waist (cm)93.9 (93.0–94.9)97.6 (95.5–99.7)99.9 (96.8–103.1)103.1 (99.7–106.6)<0.001{1} {2,3} {3,4}
Waist-to-hip ratio (cm)0.91 (0.91–0.92)0.94 (0.93–0.96)0.94 (0.92–0.96)0.95 (0.93–0.98)<0.001{1,3} {2,3,4}
BMI (kg/m2)27.4 (27.0–27.7)28.4 (27.6–29.1)29.6 (28.4–30.8)31.0 (29.7–32.3)<0.001{1,2} {2,3} {3,4}
Total cholesterol (mmol/l)5.43 (5.36–5.50)5.63 (5.47–5.79)5.38 (5.24–5.62)5.74 (5.48–6.00)0.022
HDL cholesterol (mmol/l)1.43 (1.41–1.45)1.42 (1.37–1.48)1.37 (1.29–1.45)1.32 (1.23–1.41)0.097
LDL cholesterol (mmol/l)3.44 (3.38–3.50)3.57 (3.43–3.71)3.30 (3.09–3.51)3.65 (3.42–3.88)0.047
Triglycerides (mmol/l)*1.10 (1.06–1.14)1.23 (1.13–1.34)1.41 (1.25–1.60)1.49 (1.30–1.71)<0.001{1,2} {2,3,4}
Fibrinogen (mg/dl)3.17 (3.12–3.22)3.10 (3.00–3.21)3.26 (3.09–3.42)3.27 (3.09–3.45)0.290
von Willebrand factor (IU/dl)107 (104–110)100 (94–106)113 (104–122)107 (97–117)0.076
Homocysteine (μmol/l)11.3 (10.9–11.8)12.0 (11.0–12.9)11.4 (9.9–12.8)11.4 (9.8–12.9)0.709
PAI-1 (ng/ml)25.5 (24.2–26.8)30.1 (27.2–33.0)32.5 (28.1–37.0)38.1 (33.2–43.0)<0.001{1} {2,3} {3,4}
C-reactive protein ≤1 (%)96.595.598.397.90.730
Insulin (pmol/l)45.8 (43.7–47.9)56.3 (51.0–62.3)66.8 (57.2–77.9)76.2 (64.4–90.0)<0.001{1} {2,3} {3,4}
Lipoprotein(a) (mg/l)136.9 (126.0–148.8)135.2 (112.3–162.8)109.7 (82.8–145.3)158.3 (116.1–215.9)0.353
Metabolic syndrome (%)13.257.264.475.6<0.001{1} {2,3} {4}
HOMA-IR1.31 (1.25–1.38)1.99 (1.78–2.23)1.88 (1.58–2.23)2.81 (2.33–3.40)<0.001{1} {2,3} {4}
HOMA-β22.24 (21.05–23.50)22.33 (19.75–25.25)33.08 (27.41–39.96)31.56 (25.74–38.74)<0.001{1,2} {3,4}
McAuley index8.39 (8.21–8.57)7.66 (7.26–8.05)7.19 (6.59–7.79)6.56 (5.89–7.22)<0.001{1} {2,3} {3,4}
QUICKI0.37 (0.37–0.38)0.35 (0.34–0.36)0.35 (0.34–0.36)0.33 (0.31–0.34)<0.001{1} {2,3} {4}
  • Data are n, means (95% CI), or geometric means (95% CI) for variables with skewed distribution.