Table 1—

Subject characteristics by study group

ABCDE
n1220141220
Sex (M/F)7/512/88/67/512/8
Age (years)48 (36–62)50 (42–60)54 (46–64)57 (50–66)56 (42–66)
Diabetes duration (years)8 (6–12)13 (9–15)16 (10–18)20 (12–24)
A1C (%)7.6 ± 1.27.5 ± 1.38.1 ± 1.48.0 ± 1.34.6 ± 0.8
SBP (mmHg)122 ± 14129 ± 15134 ± 16140 ± 16112 ± 8
DBP (mmHg)70 ± 875 ± 882 ± 1084 ± 1270 ± 4
Hypertension drugs25%25%29%42%0%
Insulin0%0%14%25%0%
Total cholesterol (mg/dl)160 ± 22182 ± 31190 ± 32210 ± 28146 ± 10
Serum creatinine (mg/dl)0.9 ± 0.10.9 ± 0.10.9 ± 0.12.5 ± 1.00.8 ± 0.1
UAE (μg/min)8 ± 4107 ± 71340 ± 220880 ± 6406 ± 2
Urinary NAG (IU/g creatinine)4.4 ± 2.54.7 ± 3.15.8 ± 4.29.8 ± 6.84.0 ± 2.2
Urinary-α1 microglobulin (mg/g creatinine)4.5 ± 3.85.0 ± 4.05.4 ± 4.29.5 ± 8.04.0 ± 2.8
  • Data are means ± SD or median (range). DBP, diastolic blood pressure; SBP, systolic blood pressure.