Appendix Table 1—

The effect of age, duration of diabetes, and the metabolic syndrome on the equivalence of risks associated with type 2 diabetes and prior myocardial infarction

All subjects
Men
Women
HR (95% CI)PHR (95% CI)PHR (95% CI)P
CHD death
    Age below median (<56.9 years)0.96 (0.47–1.96)0.9050.86 (0.39–1.89)0.7001.67 (0.21–13.24)0.627
    Age above median (≥56.9 years)1.00 (0.57–1.72)0.9880.81 (0.43–1.52)0.5112.14 (0.52–8.85)0.294
    Diabetes duration below median (<8 years)1.00 (0.63–1.60)0.9900.96 (0.56–1.63)0.8801.78 (0.53–5.94)0.352
    Diabetes duration above median (≥8 years)0.91 (0.58–1.43)0.6740.71 (0.42–1.19)0.1932.06 (0.64–6.66)0.228
    No metabolic syndrome0.99 (0.55–1.77)0.9680.83 (0.44–156)0.5593.52 (0.47–26.16)0.220
    Metabolic syndrome0.67 (0.34–1.30)0.2330.71 (0.32–1.56)0.3920.73 (0.17–3.11)0.667
CVD death
    Age below median (<56.9 years)1.17 (0.60–2.28)0.6380.91 (0.44–1.89)0.7972.98 (0.40–22.45)0.290
    Age above median (≥56.9 years)1.24 (0.73–2.09)0.4211.06 (0.59–1.91)0.8452.85 (0.70–11.67)0.146
    Diabetes duration below median (<8 years)1.24 (0.80–1.92)0.3271.08 (0.66–1.77)0.7652.73 (0.84–8.84)0.094
    Diabetes duration above median (≥8 years)1.17 (0.76–1.78)0.4790.88 (0.54–1.42)0.5932.96 (0.93–9.49)0.067
    No metabolic syndrome1.33 (0.75–2.34)0.3301.10 (0.59–2.05)0.7595.34 (0.73–38.92)0.098
    Metabolic syndrome0.79 (0.43–1.45)0.4490.69 (0.34–1.38)0.2951.25 (0.30–5.19)0.758
  • HRs comparing diabetic subjects without prior myocardial infarction with nondiabetic subjects with prior myocardial infarction were calculated from Cox models for CHD mortality and CVD mortality, adjusted for age, sex (all subjects), area of residence, smoking status, hypertension, total cholesterol, HDL cholesterol, and logarithm of triglycerides.