Table 2—

Incidence per 1,000 person-years and Cox model HR for CHD death (adjusted for age, area of residence, and sex) during the 18-year follow-up according to the presence of diabetes and prior evidence of CHD disease in 1,373 nondiabetic and 1,059 diabetic subjects

Prior evidence of CHDNondiabetic subjects
Diabetic subjects
Subjects with prior CHD: diabetic vs. nondiabetic
Subjects without prior CHD: diabetic vs. nondiabetic
Prior CHDNo prior CHDHR (95% CI)PPrior CHDNo prior CHDHR (95% CI)PHR (95% CI)PHR (95% CI)P
All
    Prior MI26.83.25.4 (3.4–8.7)<0.00171.426.02.7 (2.1–3.4)<0.0012.3 (1.5–3.7)<0.0017.0 (5.4–9.2)<0.001
    Angina pectoris at baseline9.83.32.9 (1.9–4.6)<0.00147.324.91.9 (1.5–2.4)<0.0014.0 (2.6–6.0)<0.0016.4 (4.8–8.4)<0.001
    ECG changes at baseline8.83.02.8 (1.9–4.3)<0.00143.323.01.9 (1.5–2.3)<0.0014.1 (2.9–5.9)<0.0016.6 (4.8–9.1)<0.001
    Any prior sign (MI, angina pectoris, or ECG change)8.12.43.4 (2.2–5.1)<0.00141.119.92.0 (1.6–2.6)<0.0014.2 (3.1–5.7)<0.0017.0 (4.8–10.1)<0.001
Men
    Prior MI34.15.85.1 (3.1–8.5)<0.00172.826.92.7 (2.0–3.6)<0.0012.0 (1.2–3.3)0.0054.3 (3.2–5.9)<0.001
    Angina pectoris at baseline18.46.13.0 (1.8–5.0)<0.00155.526.12.0 (1.5–2.7)<0.0012.6 (1.6–4.2)<0.0014.0 (2.9–5.5)<0.001
    ECG changes at baseline16.05.62.6 (1.7–4.2)<0.00148.325.11.9 (1.5–2.5)<0.0012.7 (1.8–4.0)<0.0014.3 (3.0–6.1)<0.001
    Any prior sign (MI, angina pectoris, or ECG change)15.14.73.0 (1.9–4.7)<0.00146.621.62.1 (1.6–2.7)<0.0012.8 (2.0–4.0)<0.0014.2 (2.8–6.4)<0.001
Women
    Prior MI10.81.17.3 (2.0–26.1)0.00267.725.22.5 (1.6–3.9)<0.0015.4 (1.4–20.1)0.01218.7 (10.6–32.7)<0.001
    Angina pectoris at baseline3.61.02.5 (0.9–7.0)0.07939.323.21.7 (1.2–2.4)0.0019.4 (4.0–22.0)<0.00119.2 (10.2–36.3)<0.001
    ECG changes at baseline3.10.83.7 (1.4–9.6)0.00738.320.21.7 (1.3–2.4)0.0019.6 (4.8–19.5)<0.00121.6 (10.2–45.5)<0.001
    Any prior sign (MI, angina pectoris, or ECG change)3.30.56.2 (2.0–19.2)0.00135.717.41.9 (1.3–2.7)0.0018.9 (4.9–16.0)<0.00134.4 (12.2–97.0)<0.001
  • MI, myocardial infarction.