Table 2—

Adjusted relative risk of type 2 diabetes by quarters of GGT and ALT

Adjusted relative risk of type 2 diabetes
Incidence % (no. of cases)ABC
GGT (IU/l) (n men)
    ≤18 (866)1.0 (9)1.001.001.00
    19–25 (920)2.2 (20)2.09 (0.95–4.59)2.14 (0.95–4.93)1.83 (0.80–4.20)
    26–36 (847)3.8 (32)3.72 (1.78–7.80)3.14 (1.43–6.86)2.42 (1.10–5.34)
    ≥37 (867)4.5 (39)4.52 (2.19–9.33)3.68 (1.68–8.04)2.69 (1.21–5.97)
    TrendP < 0.0001P < 0.0001P = 0.01
ALT (IU/l)
    ≤12 (1,072)1.4 (16)1.001.001.00
    13–15 (790)2.4 (19)1.59 (0.81–3.09)1.31 (0.65–2.61)1.20 (0.60–2.42)
    16–20 (742)2.8 (21)1.93 (1.00–3.73)1.60 (0.82–3.15)1.54 (0.78–3.00)
    ≥21 (896)5.0 (44)3.44 (1.91–6.21)2.72 (1.47–5.06)1.91 (1.01–3.60)
    TrendP < 0.0001P = 0.0006P = 0.11
  • Data are relative risk (95% CI). A = age-adjusted; B = adjusted for age, social class, physical activity, smoking status, alcohol intake, preexisting coronary heart disease or stroke, use of statins, and BMI; C = adjusted for above and HOMA-IR.