Table 2—

Baseline and lifetime alcohol consumption and risk of type 2 diabetes among 16,330 women

Alcohol consumptionAlcohol consumptionP value linear trendP value quadratic trend
Baseline alcohol consumption (g/day)0 (teetotaler)0–4.95.0–29.930.0–69.970.0–139.9140.0–209.9≥210
    Cases (n)10021117487925343
    Person-years9,29719,53323,75516,01514,64310,0097,998
    Age and BMI adjusted1.01.05 (0.83–1.33)0.79 (0.61–1.01)0.65 (0.49–0.87)0.82 (0.62–1.09)0.68 (0.48–0.95)0.69 (0.48–0.98)0.0070.06
    Multivariate adjusted*1.01.04 (0.80–1.34)0.86 (0.66–1.12)0.66 (0.48–0.91)0.91 (0.67–1.24)0.64 (0.44–0.93)0.69 (0.47–1.02)0.0070.25
    Multivariate adjusted1.01.02 (0.79–1.32)0.85 (0.65–1.11)0.64 (0.46–0.89)0.88 (0.63–1.23)0.61 (0.41–0.92)0.65 (0.42–1.01)0.0140.25
Lifetime alcohol consumption (alcohol-years)0 (teetotaler)0–4.95.0–9.910.0–19.920.0–29.930.0–49.9≥50
    Cases (n)101120132137759091
    Person-years9,49211,36215,59422,20012,47114,88214,104
    Age and BMI adjusted1.01.06 (0.82–1.39)0.92 (0.71–1.19)0.70 (0.54–0.91)0.76 (0.56–1.02)0.76 (0.57–1.02)0.79 (0.60–1.05)0.0030.10
    Age, BMI, and alcohol adjusted1.01.06 (0.82–1.39)0.93 (0.72–1.21)0.73 (0.56–0.95)0.82 (0.60–1.12)0.89 (0.64–1.22)1.04 (0.71–1.54)0.0060.02
    Multivariate adjusted*1.01.14 (0.86–1.50)0.96 (0.72–1.26)0.75 (0.56–0.98)0.78 (0.56–1.08)0.87 (0.57–1.06)0.80 (0.59–1.10)0.0070.26
    Multivariate and alcohol adjusted§1.01.14 (0.87–1.51)0.97 (0.74–1.28)0.78 (0.59–1.03)0.86 (0.61–1.20)0.91 (0.65–1.28)1.09 (0.73–1.64)0.0240.05
  • Data are HR (95% CI), unless otherwise indicated.

  • *

    * Adjusted for age, BMI, smoking status, education, systolic blood pressure, menopause, physical activity, family history of type 2 diabetes, daily energy intake, and hypertension.

  • Adjusted for alcohol-years (continuous) and age, BMI, smoking status, education, systolic blood pressure, menopause, physical activity, family history of type 2 diabetes, daily energy intake, and hypertension.

  • Number of years consuming one standard alcoholic beverage of 10 g alcohol daily.

  • §

    § Adjusted for baseline alcohol consumption (continuous) and age, BMI, smoking status, education, systolic blood pressure, menopause, physical activity, family history of type 2 diabetes, daily energy intake, and hypertension.