Table 1—

Baseline characteristics of patients with diabetes and hypertension.

LisinoprilDual blockade
n3738
Type 1 diabetes (n)57
Age (years)56 ± 954 ± 9
Female (n)118
Systolic blood pressure (mmHg)142.6 ± 11.0139.1 ± 11.7
Diastolic blood pressure (mmHg)82.8 ± 7.083.8 ± 10
Heart rate (bpm)74 ± 1372 ± 11
BMI (kg /m2)30 ± 529 ± 5
Urine albumin (mg/l)53 (7–675)56 (8–914)
UACR (mg/mmol)2.0 (1–134)2.1 (1–160)
Duration of diabetes (years)11 (1–43)12 (1–46)
Duration of hypertension6.3 (1–25)8.8 (1–30)
HbA1c (%)8.2 ± 1.38.4 ± 1.3
Concomitant antihypertensive treatment (n)
    None2113
    Thiazide820*
    Calcium channel blocker89
    β-Blocker56
  • Data are means ± SD and geometric mean (range), unless otherwise indicated.

  • *

    * P < 0.05 compared with the lisinopril group; χ2 test including patients in low-dose thiazide therapy and patients without concomitant antihypertensive therapy.