Table 2—

Genotype and allele frequencies of ACE I/D polymorphism in 1,281 Chinese patients with type 2 diabetes with or without occurrence of renal and cardiovascular end points

Status of renal end point
Status of cardiovascular end point
NonoccurrenceOccurrenceNonoccurrenceOccurrence
Genotype frequency
    II559 (47.3)36 (36.7)524 (45.9)71 (51.1)
    DI496 (41.9)43 (43.9)492 (43.1)47 (33.8)
    DD128 (10.8)19 (19.4)*126 (11.0)21 (15.1)
    Total number of genotypes1,183981,142139
Allele frequency
    I1,614 (68.2)115 (58.7)1,540 (67.4)189 (68.0)
    D752 (31.8)81 (41.3)744 (32.6)89 (32.0)
    Total number of alleles2,3661962,284278
  • Data are n (%). Genotype and allele frequencies were compared by χ2 test between patients with and without renal and cardiovascular end points.

  • *

    * P = 0.018,

  • P = 0.006 when the genotype and allele frequencies were compared between patients with and those without occurrence of renal end points, respectively.