Table 3—

Hypoglycemia reported at the end of each treatment period

CSII
MDI
P
SubjectsEpisodesRate*SubjectsEpisodesRate*
Symptomatic, minor, and major hypoglycemia
    Daily hypoglycemia90 (92)95610.689 (91)8259.30.0041
    Daytime hypoglycemia87 (89)7368.587 (89)5416.2<0.001
    Nocturnal hypoglycemia71 (72)2163.070 (73)2804.00.0024
Minor hypoglycemia
    Daily hypoglycemia72 (74)4476.268 (69)3875.70.2099
    Daytime hypoglycemia59 (60)3335.659 (60)2323.9<0.001
    Nocturnal hypoglycemia51 (52)1102.249 (50)1553.20.0020
Symptomatic hypoglycemia
    Daily hypoglycemia73 (75)5076.971 (72)4346.10.0506
    Daytime hypoglycemia70 (71)4035.864 (65)3054.80.0124
    Nocturnal hypoglycemia41 (42)1042.547 (48)1252.70.7211
  • Data are n (%) or n unless otherwise indicated. Nocturnal episodes occurred between midnight and 8:00 a.m.; daytime episodes occurred between 8:00 a.m. and midnight.

  • *

    * Rate is based on the number of episodes by subjects having episodes during the 5-week treatment period;

  • calculated for the rate of hypoglycemia using Poisson regression.