Table 2—

Medication use and changes over 12 months in PC case and control subjects

PC subjects (n = 92)
Control subjects (n = 88)
P value (baseline)P value (change)
BaselineChange over 12 monthsBaselineChange over 12 months
Number of medications7 [5–9]1 (−3 to 4)5 [3–7]1 (−2 to 6)<0.0010.80
Diabetes treatment
    Oral hypoglycemics only (%)72.80.068.2−2.30.520.31
    Any insulin therapy (%)8.77.611.43.40.620.33
Blood pressure treatment
    Any antihypertensive drug (%)75.013.075.09.11.00.48
    ACE inhibitor/angiotensin 2 receptor blocker therapy (%)57.619.653.48.00.650.032
Lipid-lowering therapy (%)55.44.456.81.20.880.37
Antiplatelet agents (%)65.216.342.06.90.0030.06
Drugs for vascular risk factors*2 [1–3]1 (0–2)2 [1–3]0 (−1 to 2)0.590.002
  • Data are median [interquartile range], mean difference (95% CI), or percentages of patients in each group taking drugs in each category.

  • *

    * Excluding insulin and oral hypoglycaemic agents (see text).