Table 1—

Insulin secretion and apoptosis data of HCV-negative and HCV-positive pancreatic islets

Insulin release (% insulin content)
Apoptosis
3.3 mmol/l glucose16.7 mmol/l glucoseELISA*EM†
HCV−1.7 ± 0.33.8 ± 0.5‡0.9 ± 0.12.0 ± 0.2
HCV+1.6 ± 0.32.9 ± 0.4‡§1.0 ± 0.21.8 ± 0.2

  • Data are means ± SD.

  • *

    ↵* Data are expressed as arbitrary units of optical density;

  • †

    ↵† data are expressed as percentage of apoptotic β-cell over total number of counted β-cells;

  • ‡

    ↵‡ P < 0.01 vs. 3.3 mmol/l and

  • §

    ↵§ P < 0.05 vs. 16.7 mmol/l glucose, HCV− by the two-tailed Student’s t test. ELISA, enzyme-linked immunosorbent assay; EM, electron microscopy.