Clinical characteristics of five type 1 diabetic pregnancies
| Patient | Age (years)/ white class* | HbA1c preconception/ end of pregnancy (%) | Use of glargine in pregnancy (weeks) | Glargine dose in pregnancy (IU/day) | Time of delivery (weeks) | Newborn weight (g) | Perinatal mortality and/or congenital malformation |
|---|---|---|---|---|---|---|---|
| 1 | 32/B | 7.0/6.7 | 6 | 18 | 35 | 2,220 | No |
| 2 | 26/C | 6.4/6.4 | 12 | 56 | 37 | 3,500 | No |
| 3 | 41/C | 7.0/6.2 | 8 | 18 | 38 | 4,400 | No |
| 4 | 32/D | 7.6/5.8 | 6 | 14 | 37 | 2,850 | No |
| 5 | 27/B | 8.7/5.8 | 6 | 20 | 36 | 2,360 | No |
↵* White Classification of Diabetes in Pregnancy (7). Class A: Diet alone, any duration or onset age. Class B: Onset at age ≥20 years, duration <10 years. Class C: Onset between the ages of 10 and 19 years, duration 10–19 years. Class D: Onset before the age of 10 years, duration <20 years, background retinopathy or hypertension (not pre-eclampsia). Class R: Proliferative retinopathy or vitreous hemorrhage. Class F: Nephropathy with >500 mg/day proteinuria. Class RF: Criteria for both classes R and F coexist. Class H: Arteriosclerotic hearth disease clinically evident. Class T: Prior renal transplantation. All classes below A require insulin therapy.