Table 1—

Clinical and biochemical characteristics of study subjects

Normal weightObeseType 2 diabeticP
Sex (male/female)10/1211/97/13
Race (African American/Caucasian)8/1411/911/9
Age (years)14.5 ± 0.514.6 ± 0.415.5 ± 0.40.307
BMI (kg/m2)20.2 ± 0.5*35.1 ± 1.337.8 ± 1.5<0.001
PWV (cm/s)496.9 ± 15.2*583.9 ± 26.9769.4 ± 81.7<0.001
IMT (mm)0.539 ± 0.0080.543 ± 0.0080.529 ± 0.0080.446
HbA1c (%)5.1 ± 0.15.2 ± 0.17.4 ± 0.5<0.001
Systolic blood pressure (mmHg)102.6 ± 3.3*115.8 ± 4.1123.9 ± 3.3<0.001
Diastolic blood pressure (mmHg)64.6 ± 6.1*65.1 ± 1.770.3 ± 1.5<0.001
HOMA-IS0.36 ± 0.03*0.15 ± 0.020.09 ± 0.01<0.001
Adiponectin (mg/ml)12.7 ± 1.3*6.7 ± 0.85.7 ± 0.9<0.001
hs-CRP (mg/l)0.56 ± 0.12*3.33 ± 0.773.38 ± 0.600.001
Cholesterol (mg/dl)147.6 ± 7.0*173.2 ± 7.3168.4 ± 6.70.038
LDL (mg/dl)83.1 ± 6.7*113.3 ± 7.395.0 ± 7.50.014
Triglycerides (mg/dl)80.4 ± 11.796.8 ± 8.9163.0 ± 18.6<0.001
VLDL cholesterol (mg/dl)15.6 ± 2.4*22.7 ± 3.332.7 ± 3.7<0.001
HDL cholesterol (mg/dl)48.3 ± 2.1*40.7 ± 2.241.2 ± 2.80.024
  • Data are means ± SE. Significant post-hoc comparisons with Bonferroni adjustment, P < 0.025.

  • *

    * Normal weight vs. obese;

  • obese vs. type 2 diabetic;

  • type 2 diabetic vs. normal weight.