Table 1—

Comparison of baseline and 2-year data for subjects on C therapy

Baseline2-yearChangeP
n (women/men)23 (11/12)23 (11/12)
Age (years)51 ± 2
Duration of diabetes (years)4 ± 1
Diabetes medications
    None21
    One750.62
    Two or more1417
Weight (kg)113.2 ± 4.4108.6 ± 4.2−4.6 ± 1.20.001
BMI (kg/m2)38.5 ± 1.136.9 ± 1.0−1.6 ± 0.40.001
Body fat (kg)46.8 ± 2.544.8 ± 2.2−2.0 ± 0.80.03
Lean body mass (kg)62.6 ± 3.060.0 ± 2.9−2.6 ± 0.80.002
Fasting glucose (mg/dl)158 ± 9148 ± 12−9 ± 150.56
HbA1c (%)8.1 ± 0.27.6 ± 0.2−0.5 ± 0.30.08
Resting pulse (bpm)80 ± 279 ± 2−1 ± 20.55
Systolic blood pressure (mmHg)139 ± 2132 ± 2−7 ± 30.03
Diastolic blood pressure (mmHg)77 ± 273 ± 2−4 ± 20.06
Fasting cholesterol (mg/dl)197 ± 10185 ± 9−12 ± 110.29
HDL cholesterol (mg/dl)40 ± 238 ± 2−1 ± 10.37
LDL cholesterol (mg/dl)*115 ± 8102 ± 6−13 ± 90.14
Fasting triglycerides (mg/dl)233 ± 32225 ± 43−8 ± 420.85
  • Data are means ± SE.

  • *

    * Excludes four subjects with fasting triglycerides >400 mg/dl at baseline. Conversion factors: glucose, mg/dl to mmol/l, multiply by 0.0555; cholesterol, mg/dl to mmol/l, multiply by 0.0259; triglycerides, mg/dl to mmol/l, multiply by 0.0113.