Table 2—

Plasma CRP (mg/l) according to quintiles of total magnesium intake in 11,686 initially apparently healthy women from the WHS

Magnesium intakeQuintile of magnesium intake
P for trend
1 (lowest)2345 (highest) trend
n2,3362,3392,3372,3372,337
Median intake range (mg/day)252 (113–276)293 (276–309)324 (309–341)359 (341–384)422 (384–1138)
Plasma CRP (mg/l)
    Crude1.67 (0.67–3.80)1.49 (0.59–3.37)1.39 (0.56–3.28)1.33 (0.54–3.15)1.23 (0.52–2.96)<0.0001
    Model 1*1.49 (1.43–1.56)1.37 (1.32–1.43)1.35 (1.29–1.41)1.34 (1.29–1.40)1.33 (1.28–1.39)0.0004
    Model 21.46 (1.40–1.52)1.37 (1.32–1.43)1.35 (1.30–1.41)1.36 (1.30–1.41)1.34 (1.29–1.40)0.02
    Model 31.50 (1.43–1.57)1.39 (1.34–1.45)1.35 (1.30–1.41)1.34 (1.28–1.39)1.31 (1.25–1.37)0.0003
    Model 4§1.48 (1.41–1.55)1.38 (1.33–1.45)1.35 (1.30–1.41)1.34 (1.29–1.40)1.33 (1.27–1.40)0.02
  • *

    * Data are expressed as geometric mean (95% CI) unless otherwise indicated. *Model 1 adjusted for age and BMI.

  • Model 2 additionally adjusted for smoking, exercise, total calories, alcohol use, multivitamin use, history of diabetes, history of hypertension, history of high cholesterol, and parental history of myocardial infarction before 60 years.

  • Model 3 included all covariates in model 2 and dietary intakes of total fat, cholesterol, folate, and glycemic load.

  • §

    § Model 4 additionally adjusted for dietary fiber.